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The .454 Casull () is a firearm cartridge, developed as a wildcat cartridge in 1958 by Dick Casull, Duane Marsh and Jack Fullmer. It was first announced in November 1959 by Guns & Ammo magazine. The basic design was a lengthened and structurally improved .45 Colt case. The wildcat cartridge finally went mainstream in 1997, when Ruger began chambering its Super Redhawk in this caliber. Taurus followed with the Raging Bull model in 1998 and the Taurus Raging Judge Magnum in 2010.
The .45 Schofield and .45 Colt cartridges can fit into the .454's chambers, but not the other way around because of the lengthened case (very similar to the relationship between .38 Special and .357 Magnum cartridges, as well as the .44 Special and .44 Magnum cartridges).

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